De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase.

Recent studies showing a correlation between the levels of DNA (cytosine-5-)-methyltransferase (DNA MTase) enzyme activity and tumorigenicity have implicated this enzyme in the carcinogenic process. Moreover, hypermethylation of CpG island-containing promoters is associated with the inactivation of...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Vertino, P M, Yen, R W, Gao, J, Baylin, S B
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231454/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8754856/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.8.4555
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