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Cellular transformation and malignancy induced by ras require c-jun.

ras is an important oncogene in experimental animals and humans. In addition, activated ras proteins are potent inducers of the transcription factor AP-1, which is composed of heterodimeric complexes of Fos and Jun proteins. Together with the fact that deregulated expression of some AP-1 proteins ca...

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Sonraí Bibleagrafaíochta
Main Authors: Johnson, R, Spiegelman, B, Hanahan, D, Wisdom, R
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1996
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC231449/
https://ncbi.nlm.nih.gov/pubmed/8754851
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