Inhibition of p53-mediated growth arrest by overexpression of cyclin-dependent kinases.
Rat fibroblasts transformed by a temperature-sensitive mutant of murine p53 undergo a reversible growth arrest in G1 at 32.5 degrees C, the temperature at which p53 adopts a wild-type conformation. The arrested cells contain inactive cyclin-dependent kinase 2 (cdk2) despite the presence of high leve...
Uloženo v:
| Vydáno v: | Mol Cell Biol |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
1996
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231443/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8754845/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.8.4445 |
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