Cyclin B Proteolysis and the Cyclin-dependent Kinase Inhibitor rum1p Are Required for Pheromone-induced G(1) Arrest in Fission Yeast
The blocking of G(1) progression by fission yeast pheromones requires inhibition of the cyclin-dependent kinase cdc2p associated with the B-cyclins cdc13p and cig2p. We show that cyclosome-mediated degradation of cdc13p and cig2p is necessary for down-regulation of B-cyclin–associated cdc2p kinase a...
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| Udgivet i: | Mol Biol Cell |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Cell Biology
1998
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25352/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9614176/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.9.6.1309 |
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