Functionality of major histocompatibility complex class II molecules in mice doubly deficient for invariant chain and H-2M complexes

By combining two previously generated null mutations, Ii° and M°, we produced mice lacking the invariant chain and H-2M complexes, both required for normal cell-surface expression of major histocompatibility complex class II molecules loaded with the usual diverse array of peptides. As expected, the...

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Autores principales: Tourne, Sylvie, Miyazaki, Toru, Wolf, Paula, Ploegh, Hidde, Benoist, Christophe, Mathis, Diane
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences of the USA 1997
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC23144/
https://ncbi.nlm.nih.gov/pubmed/9256469
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