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Intermediates in the Assembly and Degradation of Class I Major Histocompatibility Complex (MHC) Molecules Probed with Free Heavy Chain–specific Monoclonal Antibodies

Unassembled (free) heavy chains appear during two stages of the class I MHC molecule's existence: immediately after translation but before assembly with peptide and β(2)-microglobulin, and later, upon disintegration of the heterotrimeric complex. To characterize the structures of folding and de...

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Bibliografiske detaljer
Main Authors: Machold, Robert P., Ploegh, Hidde L.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211561/
https://ncbi.nlm.nih.gov/pubmed/8976180
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