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Major Histocompatibility Complex Class II Molecules Can Protect from Diabetes by Positively Selecting T Cells with Additional Specificities

Insulin-dependent diabetes is heavily influenced by genes encoded within the major histocompatibility complex (MHC), positively by some class II alleles and negatively by others. We have explored the mechanism of MHC class II–mediated protection from diabetes using a mouse model carrying the rearran...

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Autori principali: Lühder, Fred, Katz, Jonathan, Benoist, Christophe, Mathis, Diane
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212118/
https://ncbi.nlm.nih.gov/pubmed/9449718
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