Nitric oxide and oxidative stress (H2O2) control mammalian iron metabolism by different pathways.

Several cellular mRNAs are regulated posttranscriptionally by iron-responsive elements (IREs) and the cytosolic IRE-binding proteins IRP-1 and IRP-2. Three different signals are known to elicit IRP-1 activity and thus regulate IRE-containing mRNAs: iron deficiency, nitric oxide (NO), and the reactiv...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Pantopoulos, K, Weiss, G, Hentze, M W
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231374/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8668195/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.7.3781
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