Nitric oxide and oxidative stress (H2O2) control mammalian iron metabolism by different pathways.

Several cellular mRNAs are regulated posttranscriptionally by iron-responsive elements (IREs) and the cytosolic IRE-binding proteins IRP-1 and IRP-2. Three different signals are known to elicit IRP-1 activity and thus regulate IRE-containing mRNAs: iron deficiency, nitric oxide (NO), and the reactiv...

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Bibliographische Detailangaben
Hauptverfasser: Pantopoulos, K, Weiss, G, Hentze, M W
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC231374/
https://ncbi.nlm.nih.gov/pubmed/8668195
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