Nitric oxide and oxidative stress (H2O2) control mammalian iron metabolism by different pathways.
Several cellular mRNAs are regulated posttranscriptionally by iron-responsive elements (IREs) and the cytosolic IRE-binding proteins IRP-1 and IRP-2. Three different signals are known to elicit IRP-1 activity and thus regulate IRE-containing mRNAs: iron deficiency, nitric oxide (NO), and the reactiv...
Guardat en:
| Publicat a: | Mol Cell Biol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231374/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8668195/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.7.3781 |
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