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CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates

Selective inhibition of T cell costimulation using the B7-specific fusion protein CTLA4-Ig has been shown to induce long-term allograft survival in rodents. Antibodies preventing the interaction between CD40 and its T cell-based ligand CD154 (CD40L) have been shown in rodents to act synergistically...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Kirk, Allan D., Harlan, David M., Armstrong, Nicholas N., Davis, Thomas A., Dong, Yinchen, Gray, Gary S., Hong, Xuening, Thomas, David, Fechner, John H., Knechtle, Stuart J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1997
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23132/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9238056/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.16.8789
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