CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates

Selective inhibition of T cell costimulation using the B7-specific fusion protein CTLA4-Ig has been shown to induce long-term allograft survival in rodents. Antibodies preventing the interaction between CD40 and its T cell-based ligand CD154 (CD40L) have been shown in rodents to act synergistically...

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Autors principals: Kirk, Allan D., Harlan, David M., Armstrong, Nicholas N., Davis, Thomas A., Dong, Yinchen, Gray, Gary S., Hong, Xuening, Thomas, David, Fechner, John H., Knechtle, Stuart J.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC23132/
https://ncbi.nlm.nih.gov/pubmed/9238056
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