IL-21 Biased Alemtuzumab Induced Chronic Antibody-Mediated Rejection Is Reversed by LFA-1 Costimulation Blockade
Despite its excellent efficacy in controlling T cell mediated acute rejection, lymphocyte depletion may promote a humoral response. While T cell repopulation after depletion has been evaluated in many aspects, the B cell response has not been fully elucidated. We tested the hypothesis that the mecha...
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| Principais autores: | , , , , , |
|---|---|
| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
Frontiers Media S.A.
2018-10-01
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| 丛编: | Frontiers in Immunology |
| 主题: | |
| 在线阅读: | https://www.frontiersin.org/article/10.3389/fimmu.2018.02323/full |
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