Human interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but not high-affinity binding.

The human interleukin-3 receptor (IL-3R) is a heterodimer that comprises an IL-3 specific alpha chain (IL-3R alpha) and a common beta chain (beta C) that is shared with the receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF) and IL-5. These receptors belong to the cytokine recept...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Stomski, F C, Sun, Q, Bagley, C J, Woodcock, J, Goodall, G, Andrews, R K, Berndt, M C, Lopez, A F
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231298/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8649415/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.6.3035
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!