Human interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but not high-affinity binding.

Lignende værker

• Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF.
  af: Woodcock, J M, et al.
  Udgivet: (1994)
• Two distinct functional high affinity receptors for mouse interleukin-3 (IL-3).
  af: Hara, T, et al.
  Udgivet: (1992)
• The receptor for interleukin 3 is selectively induced in human endothelial cells by tumor necrosis factor alpha and potentiates interleukin 8 secretion and neutrophil transmigration.
  af: Korpelainen, E I, et al.
  Udgivet: (1993)
• Kinetic analysis of high affinity forms of interleukin (IL)-13 receptors: suppression of IL-13 binding by IL-2 receptor gamma chain.
  af: Kuznetsov, V A, et al.
  Udgivet: (1999)
• Impaired interleukin-3 (IL-3) response of the A/J mouse is caused by a branch point deletion in the IL-3 receptor alpha subunit gene.
  af: Ichihara, M, et al.
  Udgivet: (1995)