Human interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but not high-affinity binding.

Registos relacionados

• Two distinct functional high affinity receptors for mouse interleukin-3 (IL-3).
  Por: Hara, T, et al.
  Publicado em: (1992)
• Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF.
  Por: Woodcock, J M, et al.
  Publicado em: (1994)
• Kinetic analysis of high affinity forms of interleukin (IL)-13 receptors: suppression of IL-13 binding by IL-2 receptor gamma chain.
  Por: Kuznetsov, V A, et al.
  Publicado em: (1999)
• Interleukin 10 (IL-10) upregulates functional high affinity IL-2 receptors on normal and leukemic B lymphocytes
  Publicado em: (1993)
• An improved resolution structure of the human β common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope
  Por: Carr, P. D., et al.
  Publicado em: (2006)