WW domain sequence activity relationships identified using ligand recognition propensities of 42 WW domains

WW domains mediate protein–protein interactions in a number of different cellular functions by recognizing proline-containing peptide sequences. We determined peptide recognition propensities for 42 WW domains using NMR spectroscopy and peptide library screens. As potential ligands, we studied both...

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Main Authors: Otte, Livia, Wiedemann, Urs, Schlegel, Brigitte, Pires, José Ricardo, Beyermann, Michael, Schmieder, Peter, Krause, Gerd, Volkmer-Engert, Rudolf, Schneider-Mergener, Jens, Oschkinat, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312455/
https://ncbi.nlm.nih.gov/pubmed/12592019
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