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Mutations in the B1 domain of protein G that delay the onset of amyloid fibril formation in vitro

We previously reported that under certain experimental conditions, many variants of the B1 domain of IgG-binding protein G from Streptococcus form fibrils reproducibly. The variant I6T53 was the focus of the present study because the lag phase in the kinetics of fibril formation by this variant is s...

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Detalles Bibliográficos
Main Authors: Ramírez-Alvarado, Marina, Cocco, Melanie J., Regan, Lynne
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312443/
https://ncbi.nlm.nih.gov/pubmed/12592027
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