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In vitro unfolding, refolding, and polymerization of human γD crystallin, a protein involved in cataract formation
Human γD crystallin (HγD-Crys), a major protein of the human eye lens, is a primary component of cataracts. This 174-residue primarily β-sheet protein is made up of four Greek keys separated into two domains. Mutations in the human gene sequence encoding HγD-Crys are implicated in early-onset catara...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2312441/ https://ncbi.nlm.nih.gov/pubmed/12592018 |
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