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In vitro unfolding, refolding, and polymerization of human γD crystallin, a protein involved in cataract formation

Human γD crystallin (HγD-Crys), a major protein of the human eye lens, is a primary component of cataracts. This 174-residue primarily β-sheet protein is made up of four Greek keys separated into two domains. Mutations in the human gene sequence encoding HγD-Crys are implicated in early-onset catara...

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Hlavní autoři: Kosinski-Collins, Melissa S., King, Jonathan
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312441/
https://ncbi.nlm.nih.gov/pubmed/12592018
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