Leucine 145 of the ribotoxin α-sarcin plays a key role for determining the specificity of the ribosome-inactivating activity of the protein

Secreted fungal RNases, represented by RNase T1, constitute a family of structurally related proteins that includes ribotoxins such as α-sarcin. The active site residues of RNase T1 are conserved in all fungal RNases, except for Phe 100 that is not present in the ribotoxins, in which Leu 145 occupie...

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Hlavní autoři: Masip, Manuel, García-Ortega, Lucía, Olmo, Nieves, García-Mayoral, Ma Flor, Pérez-Cañadillas, José Manuel, Bruix, Marta, Oñaderra, Mercedes, Martínez del Pozo, Álvaro, Gavilanes, José G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312396/
https://ncbi.nlm.nih.gov/pubmed/12493839
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