Biliary and Pancreatic Dysgenesis in Mice Harboring a Mutation in Pkhd1

Autosomal recessive polycystic kidney disease is a hereditary fibrocystic disease that involves the kidneys and the biliary tract. Mutations in the PKHD1 gene are responsible for typical forms of autosomal recessive polycystic kidney disease. We have generated a mouse model with targeted mutation of...

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Main Authors: Gallagher, Anna-Rachel, Esquivel, Ernie L., Briere, Tiffany S., Tian, Xin, Mitobe, Michihiro, Menezes, Luis F., Markowitz, Glen S., Jain, Dhanpat, Onuchic, Luiz F., Somlo, Stefan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2008
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Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312372/
https://ncbi.nlm.nih.gov/pubmed/18202188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070381
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