Inhibition of Autophagy Prevents Hippocampal Pyramidal Neuron Death after Hypoxic-Ischemic Injury

Neonatal hypoxic/ischemic (H/I) brain injury causes neurological impairment, including cognitive and motor dysfunction as well as seizures. However, the molecular mechanisms regulating neuron death after H/I injury are poorly defined and remain controversial. Here we show that Atg7, a gene essential...

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Autors principals: Koike, Masato, Shibata, Masahiro, Tadakoshi, Masao, Gotoh, Kunihito, Komatsu, Masaaki, Waguri, Satoshi, Kawahara, Nobutaka, Kuida, Keisuke, Nagata, Shigekazu, Kominami, Eiki, Tanaka, Keiji, Uchiyama, Yasuo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2008
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312361/
https://ncbi.nlm.nih.gov/pubmed/18187572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070876
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