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Proofreading Activity of DNA Polymerase Pol2 Mediates 3′-End Processing during Nonhomologous End Joining in Yeast

Genotoxic agents that cause double-strand breaks (DSBs) often generate damage at the break termini. Processing enzymes, including nucleases and polymerases, must remove damaged bases and/or add new bases before completion of repair. Artemis is a nuclease involved in mammalian nonhomologous end joini...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Tseng, Shun-Fu, Gabriel, Abram, Teng, Shu-Chun
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312331/
https://ncbi.nlm.nih.gov/pubmed/18437220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000060
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