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Adenovirus E1A proteins inhibit activation of transcription by p53.

p53 stimulates the transcription of a number of genes, such as MDM2, Waf1, and GADD45. We and others have shown previously that this activity of p53 can be inhibited by adenovirus type 2 or 12 large E1B proteins. Here we show that the adenovirus E1A proteins also can repress the stimulation of trans...

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Autors principals: Steegenga, W T, van Laar, T, Riteco, N, Mandarino, A, Shvarts, A, van der Eb, A J, Jochemsen, A G
Format: Artigo
Idioma:Inglês
Publicat: 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC231197/
https://ncbi.nlm.nih.gov/pubmed/8628276
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