Inactivation of IkappaBbeta by the tax protein of human T-cell leukemia virus type 1: a potential mechanism for constitutive induction of NF-kappaB.
In resting T lymphocytes, the transcription factor NF-kappaB is sequestered in the cytoplasm via interactions with members of the I kappa B family of inhibitors, including IkappaBalpha and IkappaBbeta. During normal T-cell activation, IkappaBalpha is rapidly phosphorylated, ubiquitinated, and degrad...
Kaydedildi:
| Yayımlandı: | Mol Cell Biol |
|---|---|
| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis
1996
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231195/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628274/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.5.2083 |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|