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Protein kinase A-mediated CREB phosphorylation is an oxidant-induced survival pathway in alveolar type II cells

Oxidant stress plays a role in the pathogenesis of pulmonary diseases, including fibrotic lung disease and cancer. We previously found that hydrogen peroxide (H(2)O(2)) initiates an increase in Ca(2+)/cAMP-response element binding protein (CREB) phosphorylation in C10 alveolar type II cells that req...

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Detalhes bibliográficos
Main Authors: Barlow, Christy A., Kitiphongspattana, Kajorn, Siddiqui, Nazli, Roe, Michael W., Mossman, Brooke T., Lounsbury, Karen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2311383/
https://ncbi.nlm.nih.gov/pubmed/18392938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-008-0203-z
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