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Protein kinase A-mediated CREB phosphorylation is an oxidant-induced survival pathway in alveolar type II cells
Oxidant stress plays a role in the pathogenesis of pulmonary diseases, including fibrotic lung disease and cancer. We previously found that hydrogen peroxide (H(2)O(2)) initiates an increase in Ca(2+)/cAMP-response element binding protein (CREB) phosphorylation in C10 alveolar type II cells that req...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer US
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2311383/ https://ncbi.nlm.nih.gov/pubmed/18392938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-008-0203-z |
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