Oxidants and Signaling by Mitogen-Activated Protein Kinases in Lung Epithelium

Oxidants in cigarette smoke and generated from asbestos fibers activate mitogen-activated protein kinase (MAPK) signaling cascades in lung epithelial cells in vitro and in vivo. These signaling pathways lead to the enhanced ability of Jun and Fos family members (i.e., components of the activator pro...

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Detalhes bibliográficos
Main Authors: Mossman, Brooke T., Lounsbury, Karen M., Reddy, Sekhar P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2006
Assuntos:
Airway Epithelium, Inflammation, and Mechanisms of Disease: A Tribute to Carol B. Basbaum
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644227/
https://ncbi.nlm.nih.gov/pubmed/16484683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0047SF
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