AsialoGM1 and TLR5 Cooperate in Flagellin-Induced Nucleotide Signaling to Activate Erk1/2

Bacterial flagellin can interact with both Toll-like receptor 5 (TLR5) and the cell surface glycolipid, asialoGM1, to activate an innate immune response. The induction of mucin by flagellin in human lung epithelial cells (NCIH292) is dependent on asialoGM1 ligation, ATP receptor signaling, Ca(2+) mo...

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Detalhes bibliográficos
Main Authors: McNamara, Nancy, Gallup, Marianne, Sucher, Anatol, Maltseva, Inna, McKemy, David, Basbaum, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2006
Assuntos:
Airway Epithelium, Inflammation, and Mechanisms of Disease: A Tribute to Carol B. Basbaum
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644226/
https://ncbi.nlm.nih.gov/pubmed/16439799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0441OC
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