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A relaxed active site after exon ligation by the group I intron
During RNA maturation, the group I intron promotes two sequential phosphorotransfer reactions resulting in exon ligation and intron release. Here, we report the crystal structure of the intron in complex with spliced exons and two additional structures that examine the role of active-site metal ions...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2311373/ https://ncbi.nlm.nih.gov/pubmed/18408159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712016105 |
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