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A relaxed active site after exon ligation by the group I intron

During RNA maturation, the group I intron promotes two sequential phosphorotransfer reactions resulting in exon ligation and intron release. Here, we report the crystal structure of the intron in complex with spliced exons and two additional structures that examine the role of active-site metal ions...

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Bibliografiske detaljer
Main Authors: Lipchock, Sarah V., Strobel, Scott A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2311373/
https://ncbi.nlm.nih.gov/pubmed/18408159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712016105
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