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Two chimeric receptors of epidermal growth factor receptor and c-Ros that differ in their transmembrane domains have opposite effects on cell growth.

Two chimeric receptors, ER1 and ER2, were constructed. ER1 contains the extracellular and transmembrane (TM) domains derived from epidermal growth factor receptor and the cytoplasmic domain from c-Ros; ER2 is identical to ER1 except that its TM domain is derived from c-Ros. Both chimeras can be acti...

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Publicat a:Mol Cell Biol
Autors principals: Xiong, Q, Chan, J L, Zong, C S, Wang, L H
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231135/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8657124/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.4.1509
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