The cell cycle-coupled expression of topoisomerase IIalpha during S phase is regulated by mRNA stability and is disrupted by heat shock or ionizing radiation.

Topoisomerase II is a multifunctional protein required during DNA replication, chromosome disjunction at mitosis, and other DNA-related activities by virtue of its ability to alter DNA supercoiling. The enzyme is encoded by two similar but nonidentical genes: the topoisomerase IIalpha and IIbeta gen...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Goswami, P C, Roti Roti, J L, Hunt, C R
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 1996
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231134/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8657123/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.4.1500
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