The cell cycle-coupled expression of topoisomerase IIalpha during S phase is regulated by mRNA stability and is disrupted by heat shock or ionizing radiation.
Topoisomerase II is a multifunctional protein required during DNA replication, chromosome disjunction at mitosis, and other DNA-related activities by virtue of its ability to alter DNA supercoiling. The enzyme is encoded by two similar but nonidentical genes: the topoisomerase IIalpha and IIbeta gen...
Na minha lista:
| Udgivet i: | Mol Cell Biol |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1996
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231134/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8657123/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.4.1500 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|