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The inv(16) encodes an acute myeloid leukemia 1 transcriptional corepressor

The inv(16) is one of the most frequent chromosomal translocations associated with acute myeloid leukemia (AML). The inv(16) fusion protein acts by dominantly interfering with AML-1/core binding factor β-dependent transcriptional regulation. Here we demonstrate that the inv(16) fusion protein cooper...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lutterbach, Bart, Hou, Yue, Durst, Kristie L., Hiebert, Scott W.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23113/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10536006/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.22.12822
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