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Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation.

Extracellular stimuli that activate the transcription factor NF-kappaB cause rapid phosphorylation of the IkappaBalpha inhibitor, which retains NF-kappaB in the cytoplasm of nonstimulated cells. Phosphorylation of IkappaBalpha is followed by its rapid degradation, the inhibition of which prevents NF...

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Detalhes bibliográficos
Main Authors: DiDonato, J, Mercurio, F, Rosette, C, Wu-Li, J, Suyang, H, Ghosh, S, Karin, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC231113/
https://ncbi.nlm.nih.gov/pubmed/8657102
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