Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation.
Extracellular stimuli that activate the transcription factor NF-kappaB cause rapid phosphorylation of the IkappaBalpha inhibitor, which retains NF-kappaB in the cytoplasm of nonstimulated cells. Phosphorylation of IkappaBalpha is followed by its rapid degradation, the inhibition of which prevents NF...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231113/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8657102/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.4.1295 |
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