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Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation.

Although Rafs play a central role in signal transduction, the mechanism(s) by which they become activated is poorly understood. Raf-1 activation is dependent on the protein's ability to bind Ras, but Ras binding is insufficient to activate Raf-1 tyrosine phosphorylation to this Ras-induced activatio...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Jelinek, T, Dent, P, Sturgill, T W, Weber, M J
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231085/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8622647/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.3.1027
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