Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation.

Although Rafs play a central role in signal transduction, the mechanism(s) by which they become activated is poorly understood. Raf-1 activation is dependent on the protein's ability to bind Ras, but Ras binding is insufficient to activate Raf-1 tyrosine phosphorylation to this Ras-induced activatio...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Jelinek, T, Dent, P, Sturgill, T W, Weber, M J
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1996
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231085/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8622647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.3.1027
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