Casein kinase II phosphorylates I kappa B alpha at S-283, S-289, S-293, and T-291 and is required for its degradation.

The phosphoprotein I kappa B alpha exists in the cytoplasm of resting cells bound to the ubiquitous transcription factor NF-kappa B (p50-p65). In response to specific cellular stimulation, I kappa B alpha is further phosphorylated and subsequently degraded, allowing NF-kappa B to translocate to the...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	McElhinny, J A, Trushin, S A, Bren, G D, Chester, N, Paya, C V
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 1996
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231071/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8622692/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.3.899
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