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DNA methylation specifies chromosomal localization of MeCP2.

MeCP2 is a chromosomal protein that is concentrated in the centromeric heterochromatin of mouse cells. In vitro, the protein binds preferentially to DNA containing a single symmetrically methylated CpG. To find out whether the heterochromatic localization of MeCP2 depended on DNA methylation, we tra...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Autores principales: Nan, X, Tate, P, Li, E, Bird, A
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1996
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231017/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524323/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.1.414
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