DNA methylation specifies chromosomal localization of MeCP2.
MeCP2 is a chromosomal protein that is concentrated in the centromeric heterochromatin of mouse cells. In vitro, the protein binds preferentially to DNA containing a single symmetrically methylated CpG. To find out whether the heterochromatic localization of MeCP2 depended on DNA methylation, we tra...
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| Pubblicato in: | Mol Cell Biol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
1996
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231017/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524323/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.1.414 |
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