Unliganded thyroid hormone receptor alpha can target TATA-binding protein for transcriptional repression.

Unliganded human thyroid hormone receptor alpha (hTR alpha) can repress transcription by inhibiting the formation of a functional preinitiation complex (PIC) on promoters bearing thyroid hormone receptor (TR)-binding elements. Here we demonstrate that hTR alpha directly contacts the TATA-binding pro...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Fondell, J D, Brunel, F, Hisatake, K, Roeder, R G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231001/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524305/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.1.281
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