Unliganded thyroid hormone receptor alpha can target TATA-binding protein for transcriptional repression.
Unliganded human thyroid hormone receptor alpha (hTR alpha) can repress transcription by inhibiting the formation of a functional preinitiation complex (PIC) on promoters bearing thyroid hormone receptor (TR)-binding elements. Here we demonstrate that hTR alpha directly contacts the TATA-binding pro...
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| Опубликовано в:: | Mol Cell Biol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
1996
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231001/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524305/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.1.281 |
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