Abrogation of the alternative complement pathway by targeted deletion of murine factor B

To investigate the role of complement protein factor B (Bf) and alternative pathway activity in vivo, and to test the hypothesized potential genetic lethal effect of Bf deficiency, the murine Bf gene was interrupted by exchange of exon 3 through exon 7 (including the factor D cleaving site) with the...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Matsumoto, Mitsuru, Fukuda, Wataru, Circolo, Antonella, Goellner, Joseph, Strauss-Schoenberger, Jena, Wang, Xuefeng, Fujita, Shigeru, Hidvegi, Tunde, Chaplin, David D., Colten, Harvey R.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1997
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23097/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9238044/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.16.8720
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