Biosynthesis of the third component of complement (C3) in vitro by monocytes from both normal and homozygous C3-deficient humans.

Human monocytes synthesized the third component of complement (C3) up to 5 wk in vitro. Evidence for net C3 synthesis was based on (a) incorporation of 14C-labeled amino acids into C3 protein, (b) indentity of the allotype of C3 produced in vitro with that of the doner's serum C3, even in the presen...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Einstein, L P, Hansen, P J, Ballow, M, Davis, A E, Davis, J S, Alper, C A, Rosen, F S, Colten, H R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1977
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372447/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/332718/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108876
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