Structure-function analysis of SH3 domains: SH3 binding specificity altered by single amino acid substitutions.

SH3 domains mediate intracellular protein-protein interactions through the recognition of proline-rich sequence motifs on cellular proteins. Structural analysis of the Src SH3 domain (Src SH3) complexed with proline-rich peptide ligands revealed three binding sites involved in this interaction: two...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Weng, Z, Rickles, R J, Feng, S, Richard, S, Shaw, A S, Schreiber, S L, Brugge, J S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230813/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7565714/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.10.5627
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