A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer.

The cardiac troponin T pre-mRNA contains an exonic splicing enhancer that is required for inclusion of the alternative exon 5. Here we show that enhancer activity is exquisitely sensitive to changes in the sequence of a 9-nucleotide motif (GAGGAAGAA) even when its purine content is preserved. A seri...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Ramchatesingh, J, Zahler, A M, Neugebauer, K M, Roth, M B, Cooper, T A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230736/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7651409/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.9.4898
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!