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Dependence of globin gene expression in mouse erythroleukemia cells on the NF-E2 heterodimer.

High-level, tissue-specific expression of the beta-globin genes requires the presence of an upstream locus control region (LCR). The overall enhancer activity of the beta-globin complex LCR (beta-LCR) is dependent on the integrity of the tandem NF-E2 sites of HS-2. The NF-E2 protein which binds thes...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Kotkow, K J, Orkin, S H
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1995
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230705/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7623856/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.8.4640
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