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Identification of target genes for the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysis.

The EWS/FLI-1 fusion gene results from the 11;22 chromosomal translocation in Ewing's sarcoma. The product of the gene is one of a growing number of structurally altered transcription factors implicated in oncogenesis. We have employed a subtractive cloning strategy of representational differen...

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Détails bibliographiques
Auteurs principaux: Braun, B S, Frieden, R, Lessnick, S L, May, W A, Denny, C T
Format: Artigo
Langue:Inglês
Publié: 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC230703/
https://ncbi.nlm.nih.gov/pubmed/7623854
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