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Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting
Ewing sarcoma is an aggressive primary pediatric bone tumor, often diagnosed in adolescents and young adults. A pathognomonic reciprocal chromosomal translocation results in a fusion gene coding for a protein which derives its N-terminus from a FUS/EWS/TAF15 (FET) protein family member, commonly EWS...
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| I publikationen: | Oncotarget |
|---|---|
| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Impact Journals LLC
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4951237/ https://ncbi.nlm.nih.gov/pubmed/26848860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7124 |
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