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Identification of a novel p53 promoter element involved in genotoxic stress-inducible p53 gene expression.

p53 is recruited in response to DNA-damaging genotoxic stress and plays an important role in maintaining the integrity of the genome. We show that exposure of cells to various genotoxic agents, including anticancer drugs such as mitomycin and 5-fluorouracil, results in an increase in p53 mRNA levels...

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Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Sun, X, Shimizu, H, Yamamoto, K
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 1995
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230688/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7623839/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.8.4489
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