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Mouse mammary tumor virus/v-Ha-ras transgene-induced mammary tumors exhibit strain-specific allelic loss on mouse chromosome 4

Hybrid mice carrying oncogenic transgenes afford powerful systems for investigating loss of heterozygosity (LOH) in tumors. Here, we apply this approach to a neoplasm of key importance in human medicine: mammary carcinoma. We performed a whole genome search for LOH using the mouse mammary tumor viru...

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Autors principals: Radany, Eric H., Hong, Karen, Kesharvarzi, Sima, Lander, Eric S., Bishop, J. Michael
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC23068/
https://ncbi.nlm.nih.gov/pubmed/9238034
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